Company executives said the Syracuse plant is suitable for the smaller-scale production of clinical products and antibody-drug conjugates (ADCs), while the Songdo Bio Campus will handle large-scale antibody products via the high-titer and perfusion processes, offering a broader portfolio of options to clients.“One of Syracuse’s key strengths is its extensive experience with GMP (good manufacturing practice) approvals from many counties and its highly skilled GMP workforce,” said Yoo Hyung-duk, chief of business ramp-up at Lotte Biologics.“Through rotations between the Syracuse and Songdo plants, we aim to strengthen GMP capabilities and increase productivity at the new Songdo plant.”In addition to the new Songdo factories, Lotte also plans to build a laboratory and start a “Bio Venture Initiative” to support biotech ventures and seek technological cooperation.
SYNERGY BETWEEN SYRACUSE PLANT, SONGDO BIO CLUSTERLotte said the first domestic plant in Songdo will have a “Titer Flex Quad Bioreactor System,” a high-titer facility that combines bioreactors to enhance the efficiency and flexibility of the production process.
When the three plants are completed, Lotte will have a global production capacity of 400,000 liters, including the 40,000-liter Syracuse plant it acquired from US-based multinational pharmaceutical company Bristol Myers Squibb (BMS) in 2022.
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