About the job
BluumBio is a Berkeley-based startup engineering bacteria and plants to degrade toxic compounds and restore contaminated sites. We believe pollution is one of the greatest unmet challenges of the 21st century and are dedicated to coming up with innovative, bio-based solutions.
If you’re motivated to do good in the world and are believe synthetic biology can help, we’d love to hear from you.
Your role:
As one of our Synthetic Biologists, you will play an essential role in discovering new enzymes, optimizing enzyme activity, and engineering bacteria and/or plants to express these enzymes. You will be working with another Synthetic Biologist, an Enzyme Specialist, and a Machine Learning scientist. The successful candidate will have experience with molecular biology, cloning, and assay development. You will also have the opportunity to work on other areas of running a startup, from sitting on meetings with clients to interacting with regulators. We believe in science education and outreach and encourage all BluumBio employees to publish opinion pieces and to participate in STEM public engagement opportunities.
Responsibilities:
• Design, plan, and execute experiments to advance projects to help meet company goals
• Conduct in depth literature search to guide gene editing and enzyme optimization
• Design, build and test genetic constructs
• Model metabolic networks (desired)
• Develop high throughput (96 well) assays to quickly screen genetic constructs
• Analyze, interpret data and deliver results for time-sensitive goals
• Develop new protocols as needed
• Keep detailed records of experiments in a physical or online lab book
• Be able to manage multiple projects and deadlines
• Possibility to train and mentor junior scientists in the lab
Essential requirements:
• Ph.D in synthetic biology, bioengineering, genetics, biochemistry, or other related fields
• Demonstrated hands-on experience in recombinant DNA technology and vector design/construction for altered microbial and/or plant gene expression
• Experience with bioinformatic tools for DNA and protein sequence analysis
• Demonstrated ability to formulate hypothesis, design experiments, analyze data, interpret results, trouble-shoot experiments, prepare reports, and present results
• Excellent organizational, communication, and interpersonal skills
• Self-motivated, team-oriented, and a proactive driving force of execution
• Interest in working in a startup
Desired requirements:
• Prior experience in molecular biology, physiology, or biochemistry related to microbial and/or plant biotransformation of toxic compounds
• Experience in modeling metabolic networks
• Use of computational biology to rationally design metabolic pathways and optimize host fitness
• Experience engineering non-model organisms
• Experience with nanoparticle gene delivery
• Experience in attracting grant or other funding
• Metabolomics (LC/MS and or GC/MS)
BLUUMBIO
