Scientist / Senior Scientist (mRNA Immunotherapy Development)

Engage Bio is a Y Combinator-backed, seed-stage biotech developing mRNA immunotherapies to eliminate cancer. Our platform technology turns tumors into factories for immunotherapies. This local production improves efficacy and reduces toxicity by greatly increasing the concentration of drug within the tumor compared to distant tissues. This allows us to completely eliminate tumors while sparing healthy tissues.

We are seeking a Scientist to join our growing team. This is your chance to join a fast paced startup environment and be a key contributor to the development of next generation cancer immunotherapies.

Key responsibilities: Design and execute experimental workflows to discover and characterize novel mRNA-based immunotherapies Generate clear data packages to communicate results and inform decision making Research novel assays and technologies to help improve and accelerate Engage’s workflow

About you: A team player, ready to jump in and help wherever necessary Detail oriented, organized, and capable of working on multiple concurrent projects
Willing and able to quickly learn new skills and work with the shifting priorities of a face-paced startup Motivated to take initiative and independently drive projects

Qualifications PhD in Biology, Chemical Biology, or related field plus 1-5 years of experience Excellent written and oral communication skills Substantial wet lab experience including expertise in many of the following: Design, synthesis, and characterization of mRNA Lipid nanoparticle formulation Mammalian cell culture High-throughput, cell-based assays Flow cytometry Primary immune cell isolation Molecular cloning ELISAs and other biochemical binding assays Data analysis using Excel, Graphpad Prism, FlowJo, Python

Benefits Strong equity incentives. We are looking for teammates who will bring a strong sense of ownership to drive our work forward. Medical, dental, and vision coverage We are located at MBC BioLabs in San Carlos, an entrepreneurial hub full of the most innovative scientists in the Bay area.

*This position requires you to work in our labs at MBC Biolabs in San Carlos, CA.