SiPhox, a Khosla Ventures, Intel Capital, and Y Combinator-backed startup, is commercializing next-generation diagnostics and label-free proteomics using Silicon Photonics, a platform technology for optics miniaturization that has revolutionized the data center industry over the last two decades. SiPhox's technology provides the power of large laboratory instruments in a handheld device that accepts disposable silicon photonic chip sensors.
Role Overview: Note, there are two openings: Senior Research Scientist and Research Scientist
This is an opportunity to join a high-growth startup at its first major inflection point: We have a validated, functional, first-generation platform that is ready for commercialization and scale-up, as well as next generation development. SiPhox is embarking on an ambitious effort to develop and commercialize a large menu of immunoassay targets on its multiplexed clinical-grade, validated, at-home diagnostics platform. We are looking for a Senior Research Scientist and a Research Scientist who will collaborate with our engineers, process development, and product development teams to build this expanded menu on our platform and help bring it through validation.
Responsibilities
• Design and execute immunoassay experiments; generate and interpret data
• Summarize relevant work into written reports and presentations
• Collaborate across the organization on systems integration with reader hardware & software
• Validate assays in collaboration with the regulatory team and assist when needed with the commercialization process for the developed menu of markers.
• Collaborate with the process and chemistry team to ensure the development of robust and scalable processes for assay manufacturing and quality control.
Note: This is a fully in-person job
Qualifications
• PhD + 3 years or MS + 6 years of industry experience in biochemistry, biophysics, analytical chemistry, bioengineering or a related discipline
• Experience with immunoassay development required
• Experience working as part of a multi-disciplinary team required
• Able to resolve complex technical problems independently
• Working knowledge and practical ability in a variety of complex laboratory procedures, established techniques, instruments and equipment
• Attention to detail and good record keeping skills
• Proven key contributions to development projects and marketed products
• Familiarity with statistical principles applicable to assessment of assay performance
• Familiarity with standards applicable to assay validation preferred
• Experience in computational analysis of data sets using general purpose programming language (such as Python, R, or Matlab) preferred
• Experience with CLIA a plus
• Experience with POC/At-home devices is a plus
• Experience with label-free sensors is a plus
• Experience with biochips, microarrays, and microfluidics is a plus
Additional qualifications for Senior Research Scientist:
• PhD and 4+ years or MS and 6+ years of industry experience in biochemistry, biophysics, analytical chemistry, bioengineering, or a related discipline
• Knowledge of diagnostic product development and instrument systems preferred
• Familiarity with in vitro diagnostic (IVD) assay development, ISO 13485, and 21 CFR 820 preferred
Personal Characteristics:
• Sets and achieves tough stretch goals; delivers outstanding, measurable results
• Absolute personal integrity and credibility
• Passion for excellence
• Risk-taker who challenges conventional solutions
• Creative, thinks out of the box; thinks strategically
SiPhox
